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Table 2 Data for Makoto performance outcomes

From: Efficacy of a nootropic spearmint extract on reactive agility: a randomized, double-blind, placebo-controlled, parallel trial

 

Day 0

Day 7

Day 30

Day 90

P value

Single Step Audio Left (sec)

 PSE

1.0737 ± 0.118

1.0482 ± 0.135

1.0632 ± 0.131

1.0320 ± 0.121

0.129

 PLA

1.1180 ± 0.144

1.0751 ± 0.113

1.0765 ± 0.120

1.0554 ± 0.108

Single Step Audio Right (sec)

 PSE

1.0432 ± 0.112

1.0255 ± 0.157

1.0187 ± 0.116

1.0105 ± 0.118

0.081

 PLA

1.0867 ± 0.136

1.0626 ± 0.113

1.0450 ± 0.123

1.0219 ± 0.101

Single Step Visual Left (sec)

 PSE

0.9919 ± 0.163

0.9648 ± 0.146

0.9434 ± 0.132

0.9531 ± 0.134

0.305

 PLA

1.0284 ± 0.158

0.9774 ± 0.127

0.9731 ± 0.116

0.9592 ± 0.118

Single Step Visual Right (sec)

 PSE

0.9580 ± 0.140

0.9362 ± 0.179

0.9065 ± 0.130

0.9076 ± 0.126

0.304

 PLA

0.9840 ± 0.151

0.9520 ± 0.107

0.9455 ± 0.118

0.9185 ± 0.122

Single Step Left (sec)

 PSE

0.9577 ± 0.138

0.9215 ± 0.139

0.9309 ± 0.115

0.8935 ± 0.123

0.483

 PLA

0.9770 ± 0.127

0.9553 ± 0.114

0.9266 ± 0.116

0.9012 ± 0.099

Single Step Right (sec)

 PSE

0.9064 ± 0.128

0.9075 ± 0.122

0.8732 ± 0.116

0.8824 ± 0.104

0.306

 PLA

0.9334 ± 0.127

0.9212 ± 0.102

0.8958 ± 0.114

0.8872 ± 0.116

Stationary Hits (hits)

 PSE

28.90 ± 1.91

29.64 ± 2.73

30.75 ± 2.33

30.74 ± 2.38

0.481

 PLA

28.93 ± 2.18

29.39 ± 2.29

30.15 ± 2.28

30.30 ± 2.21

Stationary ART (sec)

 PSE

0.5681 ± 0.061

0.5384 ± 0.072

0.5256 ± 0.061

0.5209 ± 0.059

0.331

 PLA

0.5789 ± 0.064

0.5509 ± 0.059

0.5347 ± 0.055

0.5290 ± 0.051

Stationary wF Hits (hits)

 PSE

27.45 ± 1.75

28.04 ± 2.24

28.96 ± 2.08*

28.42 ± 2.54**

0.019

 PLA

27.16 ± 1.84

27.81 ± 2.09

28.09 ± 1.92

27.02 ± 3.55

Stationary wF ART (sec)

 PSE

0.6242 ± 0.069

0.5896 ± 0.060*

0.5811 ± 0.068*

0.5698 ± 0.057

0.036

 PLA

0.6422 ± 0.066

0.6141 ± 0.073

0.6033 ± 0.055

0.5914 ± 0.053

Lateral Hits (hits)

 PSE

21.81 ± 1.77

22.12 ± 2.32

22.60 ± 2.24

22.84 ± 2.26

0.187

 PLA

21.45 ± 2.02

21.79 ± 1.80

22.07 ± 1.82

22.37 ± 1.81

Lateral ART (sec)

 PSE

0.9171 ± 0.116

0.8859 ± 0.134

0.8856 ± 0.136

0.8616 ± 0.132

0.225

 PLA

0.9516 ± 0.131

0.9179 ± 0.108

0.9022 ± 0.103

0.8840 ± 0.104

Lateral wF Hits (hits)

 PSE

21.75 ± 1.73

22.22 ± 1.81

22.55 ± 1.88

22.72 ± 1.86

0.203

 PLA

21.48 ± 1.79

21.88 ± 1.68

22.07 ± 1.51

22.42 ± 1.64

Lateral wF ART (sec)

 PSE

0.9207 ± 0.124

0.8734 ± 0.103

0.8820 ± 0.116

0.8588 ± 0.116

0.150

 PLA

0.9453 ± 0.109

0.9141 ± 0.113

0.9019 ± 0.086

0.8768 ± 0.088

Multi-directional Hits (hits)

 PSE

18.95 ± 1.41

19.14 ± 1.66

19.60 ± 1.59

19.65 ± 1.56

0.143

 PLA

18.76 ± 1.49

18.87 ± 1.38

19.04 ± 1.35

19.26 ± 1.34

Multi-directional ART (sec)

 PSE

1.1276 ± 0.131

1.0979 ± 0.130

1.0908 ± 0.129*

1.0730 ± 0.131

0.079

 PLA

1.1641 ± 0.117

1.1351 ± 0.113

1.1288 ± 0.106

1.0983 ± 0.098

Multi-directional wF Hits (hits)

 PSE

18.54 ± 1.66

18.86 ± 1.86

19.25 ± 1.84**

19.39 ± 1.90*

0.020

 PLA

18.12 ± 1.41

18.34 ± 1.41

18.45 ± 1.48

18.66 ± 1.64

Multi-directional wF ART (sec)

 PSE

1.1684 ± 0.157

1.1303 ± 0.162*

1.1228 ± 0.160*

1.1025 ± 0.155

0.051

 PLA

1.2058 ± 0.139

1.1825 ± 0.132

1.1788 ± 0.124

1.1550 ± 0.140

Multi-directional wF Hits 2 min (hits)

 PSE

71.5 ± 6.7

72.4 ± 7.1

74.8 ± 7.5

75.2 ± 7.4

0.178

 PLA

70.1 ± 5.3

71.6 ± 5.7

72.1 ± 5.7

73.0 ± 6.1

Multi-directional wF ART 2 min (sec)

 PSE

1.188 ± 0.171

1.152 ± 0.169

1.133 ± 0.158

1.110 ± 0.154

0.242

 PLA

1.222 ± 0.136

1.181 ± 0.135

1.176 ± 0.124

1.160 ± 0.142

  1. Abbreviations: PSE proprietary spearmint extract, PLA placebo, wF with footplates, ART average reaction time, SD standard deviation
  2. Data are presented as mean ± SD. Treatment P values are shown. *represents p < 0.05 difference from PLA; ** represents p < 0.01 difference from PLA